dMM secretion of hyaluronic acid, dioxin can be blue or glial iron staining. Pre-treated with hyaluronidase negative. The small number of cancer can also be positive, but after dealing with hyaluronidase positive. Lung cancer mucin secretion neutral, pAS-D-positive staining. DMM and as a result of including a large number of glycogen, pAS staining can be positive, but pre-treated with amylase negative. Therefore, staining with dMM in the differential diagnosis of lung cancer in some help. However, hyaluronic acid for the water-soluble, in the fixed specimens, easily lost in the process of dyeing. And more than 50% of lung cancer do not have a neutral mucin. Therefore, staining the high false negative rate will be gradually replaced by immunohistochemistry.